Integrated Research director, Catherine Costello, has stepped down as a director after nine years with the company.
Costello will retire from the the board on September 15.
At the 2011 annual general meeting, Costello was re-elected for a third term, which she announced would be her last three-year term.
The board stated: "Costello's contribution to Integrated research has been immense, which is greatly appreciated by directors past and present," the statement said.
"During her time as a director, Ms Costello has served as chair of the nomination and remuneration committee plus been a member of both the strategy and audit and risk committees.
"Directors have accepted Ms Costello's retirement with regret and extend their best wishes to her for the future."
Integrated Research provides monitoring, business intelligence and diagnostic software.